1,3,8-triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders

• 收藏
• 分享

专利权人:

Ortho-McNeil Pharmaceutical; Inc.

发明人:

Jordan, Alfonzo,Pan, Kevin,Reitz, Allen B.

申请号：

AU2012202877

公开号：

AU2012202877A1

申请日:

2012.05.16

申请国别(地区):

AU

年份:

2012

代理人:

摘要：

#$%^&*AU2012202877A120120607.pdf#####Abstract The present invention is directed to novel 1,3,8-tiaza-spiro[4.5]decan-4-one derivatives of general formula wherein all variables are as defined herein, useful in the 5 treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. More particularly, the compounds of the present invention are useful in the treatment of disorders and conditions such as anxiety, depression, substance abuse, neuropathic pain, acute pain, migraine, asthma, cough and for improved cognition.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/