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DERIVES D'OXAZOLE ET DE THIAZOLE COMME INHIBITEURS SELECTIFS DE PROTEINES KINASES (C-KIT)
专利权人:
AB SCIENCE
发明人:
BENJAHAD, ABDELLAH,MOUSSY, ALAIN,CHEVENIER, EMMANUEL,PICOUL, WILLY,LERMET, ANNE,PEZ, DIDIER,MARTIN, JASON,SANDRINELLI, FRANCK
申请号:
CA2840029
公开号:
CA2840029A1
申请日:
2012.07.24
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to compounds of formula I or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, A, Q, W and X are as defined in the description. These compounds selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant proteine kinases implicated in a variety of human and animal diseases such as cell proliferative, metabolic, allergic, and degenerative disorders. More particularly, these compounds are potent and selective native and/or mutant c-kit inhibitors.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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