Marco Ciufolini,Camille Wermuth,Bruno Giethlen,Alain Moussy
申请号:
US13015664
公开号:
US08835435B2
申请日:
2011.01.28
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Novel compounds selected from 2-(3-aminoaryl)amino-4-aryl-thiazoles of formula (I) that selectively modulate, regulate, and/or inhibit signal transductions mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative metabolic, allergic and degenerative disorders. More particularly, these compounds are potent and selective c-kit inhibitors.