Nathaniel Richard West,Benjamin Michael Joseph Owens,Ahmed Nabil Hegazy,Fiona Margaret Powrie
申请号：
US15547154
公开号：
US20180022800A1
申请日:
2016.01.28
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The invention relates to methods of treating chronic intestinal inflammation and/or inflammatory bowel disease by administering an antagonist of oncostatin-M (OSM) and/or OSM receptor-β (OSMR). The invention also relates to methods for diagnosing or prognosing chronic intestinal inflammation and/or inflammatory bowel disease in an individual and for predicting whether or not an individual will respond to an anti-TNFα therapy. The methods comprise measuring OSM and/or OSMR in the individual.
