West, Nathaniel Richard,Owens, Benjamin Michael Joseph,Hegazy, Ahmed Nabil,Powrie, Fiona Margaret
申请号:
AU2016210996
公开号:
AU2016210996A1
申请日:
2016.01.28
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The invention relates to methods of treating chronic intestinal inflammation and/or inflammatory bowel disease by administering an antagonist of oncostatin-M (OSM) and/or OSM receptor-β (OSMR). The invention also relates to methods for diagnosing or prognosing chronic intestinal inflammation and/or inflammatory bowel disease in an individual and for predicting whether or not an individual will respond to an anti-TNFα therapy. The methods comprise measuring OSM and/or OSMR in the individual.