Andrea Leone-Bay;Destardi Moye-Sherman;Bryan R. Wilson
发明人:
Andrea Leone-Bay,Destardi Moye-Sherman,Bryan R. Wilson
申请号:
US12886226
公开号:
US08278308B2
申请日:
2010.09.20
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Drug delivery systems have been developed based on the formation of diketopiperazine carboxylate salts and microparticles containing the same. The systems may further comprise a bioactive agent. Related methods for making and using the biologically active agent delivery compositions are also provided. In certain embodiments, the pharmaceutically acceptable salts described can be formed by removal of solvent by methods including distillation, evaporation, spray drying or lyophilization.