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DIKETOPIPERAZINE SALTS FOR DRUG DELIVERY AND RELATED METHODS
专利权人:
MannKind Corporation
发明人:
Andrea Leone-Bay,Destardi Moye-Sherman,Bryan R. Wilson
申请号:
US16752939
公开号:
US20200164044A1
申请日:
2020.01.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Drug delivery systems have been developed based on the formation of diketopiperazine carboxylate salts and microparticles containing the same. The systems may further comprise a bioactive agent. Related methods for making and using the biologically active agent delivery compositions are also provided. In certain embodiments, the pharmaceutically acceptable salts described can be formed by removal of solvent by methods including distillation, evaporation, spray drying or lyophilization.
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