In some examples, a device includes sensing circuitry configured to receive one or more signals from a patient and processing circuitry configured to determine a plurality of autoregulation state values associated with a plurality of blood pressure values based on the one or more signals. The processing circuitry is further configured to determine that a first autoregulation state value of the plurality of autoregulation state values is anomalous based on other autoregulation state values of the plurality of autoregulation state values. The processing circuitry is also configured to modify the first autoregulation state value in response to determining that the first autoregulation state value is anomalous and determine an autoregulation status of the patient based on the plurality of autoregulation state values including the modified first autoregulation state value.