A system for monitoring autoregulation may include processing circuitry configured to receive a blood pressure signal indicative of an acquisition blood pressure of a patient at an acquisition site and an oxygen saturation signal indicative of an oxygen saturation of the patient. The processing circuitry may determine an altered blood pressure value indicative of a reference blood pressure of the patient at a reference site based on the blood pressure signal. The altered blood pressure value may enable a more accurate subsequent determination of a value indicative of the autoregulation status of the patient compared to an unaltered blood pressure value. In some examples, the processing circuitry may provide a signal indicative of the autoregulation status of the patient to an output device to enable a clinician to monitor the autoregulation status of the patient.
