1. A mutein of human tear lipocalin having a binding affinity for the receptor alpha IL-4 (intereleykin-4) characterized by at least one substitution in a position corresponding to amino acid p mature human tear lipocalin, selected from the group consisting of: Pro, Leu, Asn, Tyr, Lys or Glu at position 26 Lys at position 32 Trp, Asn, Val, His or Arg in position 34 Leu, Ala, His, Lys, or Met at position 56 Leu at position 58 or Lys, Ser, Gln or Pro at position 63.2. Lipocalin mutein of human tear according to claim 1, comprising: (1) a mutated amino acid residue in any one or more than one of the positions 27, 28, 30, 31, 33, 53, 57, 61, 64, 66, 80, 83, 104-106 and 108 of the linear polypeptide sequence of the mature human tear lipocalin, (2) a mutated amino acid residue in any two or more of the positions 26, 2, 32, 34, 55, 56, 58 and 63 sequences linear polypeptide sequence of mature human tear lipocalin wherein the amino acid sequence of the mutein comprises one of the following scoop NOSTA amino acid combinations: (1) Ser 26, Glu 34, Leu 55, Lys 58 (2) Ser 26, Asn 34, Ala 55, Lys 58, (3) Ser 26, Val 34, (4) Pro 26, Ser 34, (5) Pro 26, Ala 55, (6) Leu 26, Trp 34, Ala 55, (7) Leu 26, Trp 34, Ile 58, (8) Asn 26, Asp 34, (9) Asn 26 Ala 55, (10) Tyr 26, His 34, Ala 55, (11) Tyr 26, His 34, Ala 58, (12) Lys 26, Arg 34, Ala 55, (13) Lys 26, Arg 34, Asn 58 , (14) Glu 26, Gly 34, Ala 55, (15) Glu 26, Gly 34, Leu 58.3. The mutein according to claim 1 or 2, further comprising at least one of the following: Ala 31, Tyr 33, Trp 61, Ser 80, Leu 104, Pro 106, and Gln 108.4. The mutein according to claim 1 or 2, further comprising at least one of the following: Phe 53, Leu 53, Tyr 64, Met 64, Leu 66 and Asp 66.5. The mutein according to claim 1 or 2, further comprising at least one of the following: Arg 27, Cys 28, Arg 30, Ala 31, Tyr 33, Arg 57, Trp 61, Ser 80, Arg 83, Leu 104, Cys 105, Pro 106 and Gln 108.6. The mutein according to claim 1 or 2, further soda1. Мутеин липокали
