COMBINATION OF A NUCLEOSIDE POLYMERASE INHIBITOR WITH A MACROCYCLIC PROTEASE INHIBITOR AND USE THEREOF IN THE TREATMENT OF HEPATITIS C, LIVER FIBROSIS AND IMPAIRED LIVER FUNCTION (as amended)
Abel De La Rosa;Michael D. Rogers;Ellen S. Yetzer;William T. Symonds;Steven B. Porter;Patrick F. Smith;Williamson Ziegler Bradford
发明人:
Steven B. Porter,Williamson Ziegler Bradford,Patrick F. Smith,Ellen S. Yetzer,Abel De La Rosa,Michael D. Rogers,William T. Symonds
申请号：
US13203334
公开号：
US20120128628A1
申请日:
2010.02.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Embodiments disclosed in the present application relate to a composition that can include a hepatitis C viral polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof and a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof. Additional embodiments disclosed relate to methods for treating a disease condition such as a hepatitis C virus infection, liver fibrosis and/or impaired liver function with a hepatitis C viral polymerase inhibitor, or pharmaceutically acceptable salt or prodrug thereof and a hepatitis C viral protease inhibitor, or pharmaceutically acceptable salt or prodrug thereof.
