Disclosed are lacrimal inserts and their method of use for delivery of medication to the eye. The plug includes a body portion sized to pass through a lacrimal punctum and be positioned within a lacrimal canaliculus of the eyelid. The plug may contain a core, or reservoir, at least partially within the body portion comprising a therapeutic agent that is configured to controlled release into the eye and is configured for release medication via a designated port, valve, or orifice in the insert housing and inhibits diffusion of medication via the housing itself.本發明揭示淚管嵌入件及其用於將藥物投遞至眼部的使用方法。本發明之淚管塞包括一可通過淚點並置入眼瞼淚小管之主體。該淚管塞可包含一芯,或貯藏器,至少部分地在包含一治療劑之主體部分內,該治療劑係經配置以控制釋放至眼部且經配置用於經由該插入外殼上之一指定埠口、閥門或孔洞釋放藥物且防止經由該外殼本身的藥物擴散。10...外殼15...內表面25...開口35...凸緣/唇部45...貯藏器65...似圓形「箭頭」第一端/插入物100...淚管塞
