The Board of Trustees of the University of Illinois
发明人:
Burke, Martin D.,Cioffi, Alexander G.,Diaz, Katrina A.,Hou, Jennifer,Grillo, Anthony S.
申请号：
AU2015343245
公开号：
AU2015343245A1
申请日:
2015.11.03
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
Disclosed are methods for treating a disease or condition characterized by decreased expression or reduced function of an ion channel, comprising administering to a subject in need thereof a therapeutically effective amount of a pore-forming polyene macrolide or pore-forming derivative thereof. For example, the pore-forming polyene macrolide may be amphotericin B (AmB), nystatin, or natamycin. The methods can be used to treat cystic fibrosis.
