The Board of Trustees of the University of Illinois
发明人:
Martin D. Burke,Alexander G. Cioffi,Katrina A. Muraglia,Jennifer Hou,Anthony S. Grillo
申请号：
US15520452
公开号：
US20180015115A1
申请日:
2015.11.03
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Disclosed are methods for treating a disease or condition characterized by decreased expression or reduced function of an ion channel, comprising administering to a subject in need thereof a therapeutically effective amount of a pore-forming polyene macrolide or pore-forming derivative thereof. For example, the pore-forming polyene macrolide may be amphotericin B (AmB), nystatin, or natamycin. The methods can be used to treat cystic fibrosis.
