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Crystalline micronisate of tiotropium bromide
专利权人:
Boehringer Ingelheim Pharma GmbH & Co. KG
发明人:
BENDER, Helmut,GRAEBNER, Hagen,SCHINDLER, Konrad,TRUNK, Michael, Josef, Friedrich,WALZ, Michael
申请号:
DK03708206
公开号:
DK1487832T4
申请日:
2003.03.10
申请国别(地区):
DK
年份:
2018
代理人:
摘要:
A novel crystalline, micronized form (I) of tiotropium bromide (TTB) has particle size X 5 0 of 1-3.5 Microm, a Q ( 5.8) value of more than 60%, a specific surface of 2-5 m 2>;/g, a specific heat of solution of more than 65 Ws/g and a water content of 1-4.5%. Independent claims are also included for: (1) the production of (I); (2) medicaments (specifically inhalable powders) containing (I); (3) preparation of inhalable powders; and (4) capsules (inhalettes') containing inhalable powders. ACTIVITY : Antiasthmatic; antiinflammatory. MECHANISM OF ACTION : Anticholinergic.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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