Trunk, Michael,Walz, Michael,Bender, Helmut,Graebner, Hagen,Schindler, Konrad
申请号：
HUE07102206
公开号：
HUE031876T2
申请日:
2003.03.10
申请国别(地区):
HU
年份:
2017
代理人:
摘要：
A novel crystalline, micronized form (I) of tiotropium bromide (TTB) has particle size X 5 0 of 1-3.5 Microm, a Q ( 5.8) value of more than 60%, a specific surface of 2-5 m 2>；/g, a specific heat of solution of more than 65 Ws/g and a water content of 1-4.5%. Independent claims are also included for: (1) the production of (I)； (2) medicaments (specifically inhalable powders) containing (I)； (3) preparation of inhalable powders； and (4) capsules (inhalettes') containing inhalable powders. ACTIVITY : Antiasthmatic； antiinflammatory. MECHANISM OF ACTION : Anticholinergic.
