And benzothiazine derivatives novel infectious diseases (animals and humans) that are caused by bacteria, the present invention relates to the use of said derivatives as antimicrobial agents in diseases Hansen such as tuberculosis (TB) which is caused by mycobacteria, particularly about the door. The present invention aims as tuberculosis drug new potential to overcome the problems intolerance and pharmaceutically resistance on (drug intolerance), and to create new compounds with activity against mycobacteria. Solution of the present invention provides a compound of formula I [Omitted] (Wherein, independently of one another,R 2 and R 1 is, NO 2, CN, CONR 7 R 8, COOR 9, CHO, halogen, NR 7 R 8, SO 2 NR 7 R 8, SR 9, OCF 3 , or is there a trifluoromethyl mono, di or Independently of one another, R 4 and R 3 is an aliphatic group having 1 to 7 chain constituent elements of the branched cycloalkyl having 3 to 6 carbon atoms, benzyl unsaturated H, or a saturated, linear or, SR 9, or be in the OR 9 Independently of one another, saturated or unsaturated, is a non-halogenated or halogenated, aliphatic group having 1 to 8 chain constituent elements of branched, R 6 and R 5 is 3 to carbon atoms or straight-chain cycloalkyl of 6, or or a phenyl, a divalent group taken together R 5 and R 6 is - (CR 9 2) m - or depict the divalent taken together R 5 and R 6 based [9] of (Wherein, m is 1 to 4) (wherein, 1-4 x) mono or saturated or unsaturated substituted with (R10) x or show a, N, S, the heteroatom is O denotes a divalent group having a poly-heterocyclic ring Independently of one another, unsaturated H, or saturation, it is non-halogenated or halogenated, R 9 and 7, R 8 R is an aliphatic group having 1 to 7 chain constituent elements of linear or branched , trifluoromethyl mono, di or halogen, Or phenyl, divalent group taken together and R 4 R 3 - (CH 2) n - (wherein, n is 2 to 7) show the Unsaturated H, or saturated, the non-halogenated or halogenated, aliphatic group having 1 to
