An embolic protection system may include a guidewire having a length, at least a portion of the guidewire having a non-circular cross-sectional shape, and an embolic protection device including a mounting sleeve configured to attach the embolic protection device to the portion of the guidewire having the non-circular cross-sectional shape. The mounting sleeve may include a non-circular interior cross-sectional shape and a non-circular exterior cross-sectional shape.