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Tris - (hetero) aryl pyrazoles and their use
专利权人:
АЙКУРІС ГМБХ & КО. КГ
发明人:
Вільдум Штеффен,Кленке Буркхард,Вендт Астрід
申请号:
UAA201502210
公开号:
UA112488C2
申请日:
2013.08.16
申请国别(地区):
UA
年份:
2016
代理人:
摘要:
Procedures for their preparation, to their use for prophylaxis and / or treatment of diseases, in particular of Retroviral diseases in humans and animals.Claim 1: Compound of the formula (1), which represents a group of the formula (2) which represents nitrogen or carbon or nitrogen can be substituted with an alkyl Substituent at the carbon can be substituted with 1 to 2 alkyl substituents that Selection An independently of one another, or an oxo Substituent; v represents nitrogen or carbonThe Carbon can be replaced with a Substituent selected from the group consisting of halogen, Hydroxy, amino, methoxy, Methyl and trifluoromethyl; W represents the Carbon Carbon or nitrogen can be substituted with a Substituent selected from the group consisting of hal u00f3ge No, amino, Hydroxy, methoxy, Methyl and trifluoromethyl; X represents a nitrogen or carbonThe Carbon can be replaced with a Substituent selected from the group consisting of halogen, Hydroxy, amino, methoxy, Methyl and trifluoromethyl; and * is the liaison with the carbon Atom; r u00b9 represents phenyl or substituted phenyl piridilo, preferably 1 to 3, 1 2 SubstituentThe substituents and independently of the group consisting of halogen, Hydroxy, amino, cyano, Nitro, c u2081 u208b u2084 c u2083 u208b u2086 cycloalkyl alkyl, alkoxy, and alquilamino c u2081 u208b u2084 c u2081 u208b u2084, in which alkyl, cycloalkyl, alquilamino alkoxy and can in turn be m Ono to potency of the Tri substituted Compounds, equally or differently, with Remnants of the selected Series of halogen, Hydroxy, cyano,C u2081 u208b u2084 alkoxy, amino, mono -, di - alquilamino c u2081 u208b u2084, alquilamino c u2081 u208b u2084, cycloalkyl c u2083 u208b u2087 and heterociclilo 4 to 7 members, can be replaced with 1 or 2 piridilo substituents and the substituents independently of the group consisting of Hauls Hydrogen, Hydroxy, amino, cyano, Nitro, c u2081 u208b u2084 alkoxy alkyl, cycloalkyl c u2083 u208b u2086 and c u2081 u208b u2084,A
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