WAGNER SUSANNE,TAUPITZ MATTHIAS,SCHELLENBERGER EYK,SCHNORR JÖRG,EBERT MONIKA,GENTER GESCHE,KRATZ HARALD
申请号：
IN1523/DELNP/2014
公开号：
IN2014DN01523A
申请日:
2014.02.27
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
The present invention relates to a phosphate adsorbent on the basis of maghemite or maghemite/magnetite comprising (i) an iron oxide core comprising a crystal structure of inverse spinel iron oxide (ii) a coating selected from monomeric carbohydrates in particular monosaccharides or disaccharides alditols or mixtures thereof and/or (iii) a pharmaceutical excipient selected from polymeric carbohydrates wherein the phosphate adsorbent has the form of nanoparticles with a particle size of the iron oxide core (i) of less than 20 nm. The present invention further relates to a method for the production of a phosphate adsorbent on the basis of maghemite or maghemite/magnetite to pharmaceutical compositions comprising the phosphate adsorbent and to medical uses thereof especially for the prevention and/or treatment of hyperphosphatemia.
