Wagner, Susanne,Taupitz, Matthias,Schellenberger, Eyk,Schnorr, Jorg,Ebert, Monika,Genter, Gesche,Kratz, Harald
申请号：
AU2012306775
公开号：
AU2012306775A2
申请日:
2012.09.03
申请国别(地区):
AU
年份:
2014
代理人:
摘要：
The present invention relates to a phosphate adsorbent on the basis of maghemite or maghemite/magnetite comprising (i) an iron oxide core comprising a crystal structure of inverse spinel iron oxide, (ii) a coating selected from monomeric carbohydrates, in particular monosaccharides or disaccharides, alditols, or mixtures thereof, and/or (iii) a pharmaceutical excipient selected from polymeric carbohydrates, wherein the phosphate adsorbent has the form of nanoparticles with a particle size of the iron oxide core (i) of less than 20 nm. The present invention further relates to a method for the production of a phosphate adsorbent on the basis of maghemite or maghemite/magnetite, to pharmaceutical compositions comprising the phosphate adsorbent, and to medical uses thereof, especially for the prevention and/or treatment of hyperphosphatemia.
