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БЕСКЛЕТОЧНАЯ ОРГАНИЧЕСКАЯ ТКАНЬ, ПОДГОТОВЛЕННАЯ ДЛЯ ВОССТАНОВЛЕНИЯ ЖИЗНЕСПОСОБНОСТИ И СПОСОБЫ ЕЕ ПОЛУЧЕНИЯ
专利权人:
ТЕЛЕА БИОТЕК С.Р.Л. (IT)
发明人:
МАРЦАРО Маурицио (IT)
申请号:
RU2012122071/15
公开号:
RU2012122071A
申请日:
2010.10.29
申请国别(地区):
RU
年份:
2013
代理人:
摘要:
1. A process for preparing an acellular organic animal or human tissues for the restoration of viability, in particular for the introduction of live cells, comprising the step of in said acellular organic tissue (2 12) perform a plurality of holes (4 14) extending through its surface (8 18) and entering into the fabric (2 12), wherein said plurality of apertures (4 14) is performed using a single needle or set of needles, characterized in that said holes (4 14) overlap at least partially thus forming a hole (4 14), which communicate, at least partially, with one another.2. A method according to claim 1, characterized in that it further comprises a step in which a fabric (12) provide a cavity reservoir (20) which communicate with at least part of the holes (14).3. The method of claim 1 or 2, characterized in that said holes and / or cavities reservoirs is accomplished by one or more metal needles connected to an electric power source, created at the end of each needle of such intensity electric current waveform and to apply a sufficient amount of energy to break the bonds that connected molecule organic tissue near the end of the needle.4. A method according to claim 3, characterized in that the electric current determined by the voltage frequency of 4 Hz, while the applied sinusoidal voltage is distorted sine wave and consequently with harmonics at least first, second and third order.5. The method of claim 1 or 2, characterized in that said holes (4 14) have a diameter of at least 50 microns.6. A method according to claim 2, characterized in that said reservoir chamber (20) are substantially cylindrical and have a diameter of 1 mm.7. The method of claim 1 or 2, characterized in that the holes (4 14) have different diameters.8. A method according to claim 2, characterized in that said reservoir chamber (20) have different diameters.9. The method of claim 1 or 2, characterized in that it comprises a step in which the holes (4 14) using suction systems introduce variou
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