БХАТИА Мохит Б. (US),ХЭРИРИ Роберт Дж. (US),ХОФГАРТНЕР Вольфганг (US),ВАН Цзя-Лунь (US),Е Цянь (US)
申请号:
RU2015112289
公开号:
RU2015112289A
申请日:
2013.09.03
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A method of forming a three-dimensional tissue, which includes applying at least one cell composition and extracellular matrix (BKM) to a surface on or in a subject. The method of claim 1, wherein said cell composition and said BKM are applied to said surface. The method of claim 1, wherein said cell composition and said BKM are applied to said surface by a seal. The method of claim 1, wherein said surface is an artificial surface. The method of claim 1, wherein said artificial surface is a prosthetic device or structure. The method of claim 1, wherein said surface is a cell-deprived tissue or an organ-deprived organ. The method according to any one of paragraphs. 1-6, where the specified surface is a surface outside the specified subject. The method according to any one of paragraphs. 1-6, where the specified surface is the surface inside the specified subject. The method of claim 8, wherein said surface is a surface within the body cavity, bone, or organ of said subject. The method according to claim 1, which includes scanning the specified surface in or on the specified subject in order to form a surface map, and using the specified surface map in order to direct the specified application. The method of claim 10, wherein said scanning comprises using a laser, electron beam, magnetic resonance imaging, microwaves, X-rays, or computed tomography. The method of claim 1, wherein said BKM comprises mammalian BKM, mollusk BKM, fish BKM and or BKM plants. The method of claim 12, wherein said mammalian BKM is placental BKM. The method of claim 13, wherein said B1. Способ формирования трехмерной ткани, который включает нанесение по меньшей мере одной клеточной композиции и внеклеточного матрикса (BKM) на поверхность на или в субъекте.2. Способ по п. 1, где указанную клеточную композицию и указанный BKM наносят на указанную поверхность.3. Способ по п. 1, где указанная клеточная композиция и указанный BKM наносят на указанную поверхность печатью.4. Способ по п. 1, где ук