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Biodegradable Linkers for Molecular Therapies
专利权人:
Ivan Alferiev
发明人:
Ivan Alferiev,Robert J. Levy,Ilia Fishbein
申请号:
US13306459
公开号:
US20120141419A1
申请日:
2011.11.29
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A method and a composition for delivery of a biomaterial to an animal cell or a tissue, the composition includes (a) a biomaterial (b) a biodegradable cross-linker portion having a hydrolyzable bond, wherein the biodegradable cross-linker portion is covalently bound to the biomaterial and (c) a substrate, wherein the substrate is covalently bound to the biodegradable cross-linker portion, provided that the biodegradable cross-linker is adapted to hydrolyze by breaking the hydrolyzable bond and thereby release and deliver the biomaterial. A process of making the composition is also provided.
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