CHRISTENSEN, SIEGFRIED, BENJAMIN, IV (DECEASED),QIN, DONGHUI,JOSHI, HEMANT,TANGIRALA, RAGHURAM
申请号：
ZA201308569
公开号：
ZA201308569B
申请日:
2013.11.14
申请国别(地区):
ZA
年份:
2014
代理人:
摘要：
This invention relates to novel compounds which are inhibitors of acyl coenzymeA: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the prevention or treatment of diseases related to DGAT-1 dysfunction or where modulation of DGAT-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, hypertriglyceridemia, hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, hepatitis C virus infection and acne or other skin disorders.
