Donghui Qin;Siegfried Benjamin Christensen;Hemant Joshi;Raghuram S. Tangirala;Siegfried Benjamin Christensen, IV; IV;Rowena Christensen
发明人:
Siegfried Benjamin Christensen, IV,Donghui Qin,Hemant Joshi,Raghuram S. Tangirala
申请号：
US14118913
公开号：
US09242929B2
申请日:
2012.05.18
申请国别(地区):
US
年份:
2016
代理人:
摘要：
This invention relates to novel compounds which are inhibitors of acyl coenzymeA: diacylglycerol acyltransferase 1 (DGAT-1), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the prevention or treatment of diseases related to DGAT-1 dysfunction or where modulation of DGAT-1 activity may have therapeutic benefit including but not limited to obesity, obesity related disorders, hypertriglyceridemia, hyperlipoproteinemia, chylomicronemia, dyslipidemia, non-alcoholic steatohepatitis, diabetes, insulin resistance, metabolic syndrome, hepatitis C virus infection and acne or other skin disorders.
