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2-acylaminopropoanol-type glucosylceramide synthase inhibitors
专利权人:
Cassandra A. Celatka;Richard Silva;Craig Siegel;John Kane;Edward Lee;Yibin Xiang;Junkai Li;Thomas H. Jozafiak;Cecilia M. Bastos;Lisa M. Cuff;David J. Harris;Angeles Dios;Frederic Vinick;Mikaela Levine
发明人:
Craig Siegel,Cecilia M. Bastos,David J. Harris,Angeles Dios,Edward Lee,Richard Silva,Lisa M. Cuff,Mikaela Levine,Cassandra A. Celatka,Thomas H. Jozafiak,Frederic Vinick,Yibin Xiang,John Kane,Junkai Li
申请号:
US13122135
公开号:
US08309593B2
申请日:
2009.10.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound for use in treating polycystic kidney disease is represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. A pharmaceutical composition comprises a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. A method of treating polycystic kidney disease in a subject in need thereof comprises administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof. Methods of treating in polycystic kidney disease in a subject in need thereof respectively comprise administering to the subject a therapeutically effective amount of a compound represented by Structural Formula (I) or a pharmaceutically acceptable salt thereof.
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