CYSTEINE PROTEASE INHIBITORS

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专利权人:

MEDIVIR AB

发明人:

NILSSON, MAGNUS,ODEN, LOURDES,KAHNBERG, PIA,GRABOWSKA, URSZULA

申请号：

MYPI 20095560

公开号：

MY149191A

申请日:

2008.06.26

申请国别(地区):

MY

年份:

2013

代理人:

摘要：

COMPOUNDS OF THE FORMULA II: WHEREIN R2 IS THE SIDE CHAIN OF LEUCINE, ISOLEUCINE, CYCLOHEXYLGLYCINE, 0-METHYL THREONINE, 4-FLUOROLEUCINE OR 3-METHOXYVALINE； R3 IS H, METHYL OR F； RQ IS TRIFLUOROMETHYL AND RQ' IS H OR RQ AND RQ' DEFINE KETO； Q IS A P-(C1-C6ALKYLSULPHONYL)PHENYL- OR AN OPTIONALLY SUBSTITUTED 4-(C1- C6ALKYL)PIPERAZIN-1-YL-THIAZOL-4-YL- MOIETY HAVE UTILITY IN THE TREATMENT OF DISORDERS CHARACTERIZED BY INAPPROPRIATE EXPRESSION OR ACTIVATION OF CATHEPSIN K, SUCH AS OSTEOPOROSIS, OSTEOARTHRITIS, RHEUMATOID ARTHRITIS OR BONE METASTASES.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/