TISSU HEPATIQUE ENCAPSULE

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专利权人:

VALORISATION-HSJ, LIMITED PARTNERSHIP;THE REGENTS OF THE UNIVERSITY OF MICHIGAN;VALORISATION-HSJ; LIMITED PARTNERSHIP

发明人:

PAGANELLI, MASSIMILIANO,RAGGI, CLAUDIA,SHIKANOV, ARIELLA

申请号：

CA3043509

公开号：

CA3043509A1

申请日:

2017.11.23

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present disclosure provides an encapsulated liver tissue that can be used in vivo to improve liver functions, in vitro to determine the hepatic metabolism and/or hepatotoxicity of an agent and ex vivo to remove toxic compounds from patients' biological fluid. The encapsulated liver tissue comprises at least one liver organoid at least partially covered with a biocompatible cross-linked polymer. Processes for making the encapsulated liver tissue are also provided.

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