COMPOSITION FOR INHIBITING CYTOCHROME P450 COENZYME农业专利-农业学术服务平台

专利权人:: 충남대학교산학협력단;경북대학교 산학협력단;KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION;THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY (IAC)

发明人:: LIU, KWANG HYEONKR,류광현,SONG, GYU YONGKR,송규용,O, YU SEOKKR,오유석,WU ZHEXUECN,오철학,PHUC NGUYEN MINHVN,푸누엔민,LIU, KWANG HYEON,SONG, GYU YONG,O, YU SEOK,WU ZHEXUE,PHUC NGUYEN MINH

摘要：: The present invention relates to a composition for inhibiting a cytochrome P450 coenzyme. According to an embodiment of the present invention, by using the disclosed compound, it is possible to effectively inhibit activities of cytochrome 450 2B6, cytochrome 450 2C8, cytochrome 450 2C9, cytochrome 450 2D6, and cytochrome 450 2J2. To this end, the composition contains a compound represented by the chemical formula 1, a salt thereof, or a solvate thereof.COPYRIGHT KIPO 2018본 발명은 시토크롬 P450 동효소 억제용 조성물에 관한 것으로, 본 발명의 일 실시예에 개시된 화합물을 이용하면 시토크롬 450 2B6, 시토크롬 450 2C8, 시토크롬 450 2C9, 시토크롬 450 2D6 및 시토크롬 450 2J2의 활성을 효과적으로 저해할 수 있다.