THE BOARD OF REGENTS FOR OKLAHOMA STATE UNIVERSITY
发明人:
KAPIL SANJAY,COOPER EMILY
申请号：
NZ61457108
公开号：
NZ614571A
申请日:
2008.06.12
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed is a method of vaccinating domestic dogs and puppies, wild canids, wolves, wild dogs, domestic cats and kittens, wild cats, minks, red pandas, foxes, lions, tigers, animals in zoos or protected areas and animals in research facilities against parvovirus infection, comprising the step of administering to said animal a parvovirus vaccine comprising SEQ ID NO: 2 or a portion of SEQ ID NO: 2 that encodes an antigenic region and SEQ ID NO: 4 or a portion of SEQ ID NO: 4 that encodes an antigenic region. Further disclosed is a recombinant expression vector comprising a nucleic acid encoding a canine parvovirus VP-2 protein, wherein said nucleic acid sequence is a nucleic acid sequence selected from the group consisting of: a sequence that is at least 95% homologous to SEQ ID NO: 2 wherein nucleotides 16-18 are CTG to encode Leu at position 431 of a VP-2 protein and a sequence that is at least 95% homologous to SEQ ID No:4 wherein nucleotides 43-45 are GCA to encode Ala at position 440 of a VP-2 protein.
