A device for the administration of carboxytherapy (1) is provided comprising: a pressure container (2) for carbon dioxide defining an internal volume (2a), control means (3) and command means (4) for the device (1), an injection needle (5), suitable for subcutaneous insertion and defining an internal channel (5a), a channelling circuit (6) in a fluidic through connection with the internal volume (2a) of the pressure container (2) and with the internal channel (5a) of the injection needle (5), the channelling circuit (6) comprises an output valve (60), suitable to open or close the channelling circuit (6) in which the output valve (6) is suitable to open or close the channelling circuit (6) with an activation frequency greater than 0.5 Hz and with a flow greater than 100 cm<；sup>；3<；/sup>；/min.
