Sulfolobal Phosphotriesterase-Like (PLL) lactonases activity having enhanced properties and the uses thereof

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专利权人:

发明人:

申请号：

EP13305483.3

公开号：

EP2789344A1

申请日:

2013.04.12

申请国别(地区):

EP

年份:

2014

代理人:

摘要：

The present invention provides mutated hyperthermophilic PTE having a lactonase activity derived from a hyperthermophilic phosphotriesterase corresponding to the consensus sequence of SEQ ID NO: 1, said mutated PTE comprising the at least one mutation choosen amongst 53 putative positions and said mutated PTE having enhanced properties. Also provided are compositions comprising the mutated hyperthermophilic PTE and the uses thereof, notably as bioscavenger of organophosphate compounds or as quorum quencher of the bacteria using lactones to communicate.

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