Eric Chabriere,Mikael Elias,Julien Hiblot,Didier Raoult
申请号：
US14782703
公开号：
US10072252B2
申请日:
2014.04.14
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Mutated hyperthermophilic PTE having a lactonase activity derived from a hyperthermophilic phosphotriesterase corresponding to the consensus sequence of SEQ ID NO: 1, the mutated PTE including the at least one mutation chosen amongst 53 putative positions and the mutated PTE having enhanced properties. Also provided are compositions including the mutated hyperthermophilic PTE and the uses thereof, notably as bioscavenger of organophosphate compounds or as quorum quencher of the bacteria using lactones to communicate.
