Sutter West Bay Hospitals;Catholic Healthcare West, doing Business as St. Mary's Medical Center
发明人:
Yang, Li-Xi
申请号:
AU2006304811
公开号:
AU2006304811B2
申请日:
2006.10.19
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Camptothecin-based compounds are useful for treating a neoplasm in mammaliansubjects by administering such compound to the subjects in combination withradiotherapy, i.e., the treatment of tumors with radioactive substances orradiation from a source external to the subject. Camptothecin-based compoundsare modified by positioning at least one electron-affinic group around the camptothecinstructure to enhance their value in combination with radiotherapy. New Camptothecin-basedcompounds are disclosed that are useful for treating cancer by administeringthe novel compounds alone or in combination with radiotherapy.