Camptothecin derivatives as chemoradiation sensitizers

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专利权人:

サッター・ウエスト・ベイ・ホスピタルズ;サッター・ウエスト・ベイ・ホスピタルズ;カソリック・ヘルスケア・ウエスト・ドゥーイング・ビジネス・アズ・セント・メアリーズ・メディカル・センター

发明人:

リ－シ・ヤン,リ-シ・ヤン

申请号：

JP2008536850

公开号：

JP5328357B2

申请日:

2006.10.19

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to the subject. Camptothecin-based compounds are modified by positioning at least one electron-affinic group around the camptothecin structure to enhance their value in combination with radiotherapy. New Camptothecin-based compounds are disclosed that are useful for treating cancer by administering the novel compounds alone or in combination with radiotherapy.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/