Michael Bech Jensen,Birthe Lykkegaard Hansen,Troels Kornfelt,Kirsten Kramer Jakobsen
申请号：
US11284709
公开号：
US08536127B2
申请日:
2005.11.22
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Provided are storage containers for proteinaceous pharmaceutical compositions which are characterized in, among other things, comprising (i) a wall portion, wherein an inner wall material thereof is selected from silica-coated glass, silicone-coated glass, polymers of non-cyclic olefins, cycloolefin polymers and cycloolefin/linear olefin copolymers and (ii) one or more closure portions not constituting part of the wall portion, and which contains a formulation of a protein. Also provided are new methods of storing proteinaceous compositions. In one aspect, the stored protein is characterized as having an amino-terminal γ-carboxyglutamic acid (Gla) domain with 9-12 Gla residues.
