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STERILE ALGINATE-BASED AQUEOUS COMPOSITION FOR MEDICAL USE AND PROCESS FOR THE PREPARATION THEREOF
专利权人:
发明人:
申请号:
EP11708587.8
公开号:
EP2544695B1
申请日:
2011.03.08
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
The present invention relates to ready-to-use sterile, alginate-based, aqueous compositions for medical use. More particularly, the invention relates to an aqueous composition for medical use that has been sterilized by heat sterilization and having a viscosity at 25° C. of at least 300 cP) (Helipath® T F spindle, 100 rpm at 25° C.), said composition having a pH in the range of 6.5-7.5 containing 0.5-10 wt. % of an alginate salt and further containing 10-500 mM of one or more dissolved C2-C7 mono- or dicarboxylates that are optionally substituted with up to 2 hydroxyl groups. The alginate-based composition of the present invention has excellent storage stability and is easy to manufacture. The alginate-based aqueous compositions of the present invention can advantageously be used, for instance, to prevent adhesions between a healing trauma site and adjacent surrounding tissue. These compositions can further be used in implants or in pharmaceutical preparations for oral administration.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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