Carbonic acid of 4-aza, 5-aza, 7-aza and 4, 7-diaza-benzimidazoles and 4, 7-diaza-benzimidazoles are used as GLP-1 adjuvants for the treatment or prevention of ustiles for cardiac metabolic diseases
Aspnes, Gary Erik,Bagley, Scott W.,Curto, John M.,Dowling, Matthew S.,Edmonds, David James,Flanagan, Mark E.,Futatsugi, Kentaro,Griffith, David A.,Huard, Kim,Ingle, Gajendra,Jiao, Wenhua,Limberakis, C
申请号：
CU20190056
公开号：
CU20190056A7
申请日:
2017.12.01
申请国别(地区):
CU
年份:
2020
代理人:
摘要：
The invention relates to 6 kinds of benzoic acid and carbonic acid of 4-aza, 5-aza, 7-aza and 4.7-diaza-benzimidazoles as GLP-1R agent, the general formula is I: lt； / P gt； P gt； frumula lt space； / P gt； P gt； tools for treating or preventing metabolic diabetes and other heart diseases, Pre diabetes, nonalcoholic hepatitis and cardiovascular disease； / P gt；<；p>；La presente invención se refiere a 6 ácidos carboxílicos de benzimidazoles y 4-aza, 5-aza, 7-aza y 4,7-diaza-benzimidazoles como agonistas de GLP-1R, de fórmula general I:<；/p>； <；p>；ESPACIO PARA LA FÓRMULA<；/p>； <；p>；útiles en el tratamiento o prevención de enfermedades cardiometabólicas como diabetes, pre-diabetes, esteatohepatitis no alcohólica y enfermedad cardiovascular.<；/p>；
