An implant for repairing a segmental defect in a subject's bone at a segmental defect site, the implant comprising a scaffold for implantation at the segmental defect site and the implant optionally comprising: a plate for internal fixation, the plate being attachable to or integral with the scaffold, and the plate having means for securing it to bone outside of the segmental defect site； a hollow cavity within the scaffold； a plurality of longitudinal channels within the scaffold； and or a membrane received around the scaffold.
