LAWRENCE LIVERMORE NATIONAL SECURITY, LLC;MERCK SHARP & DOHME CORP.
发明人:
Allen John Borchardt,Daniel Bensen,Douglas Phillipison,Felice C. Lightstone,John Finn,Junhu Zhang,Leslie William Tari,Michael Trzoss,Min Teng,Sergio E. Wong,Suk Joong Lee,Thanh To Lam,Toan B. Nguyen,V
申请号：
BR112016005361
公开号：
BR112016005361A8
申请日:
2014.09.10
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
Summary Tricyclic gyrase inhibitors disclosed herein are compounds having the structure of formula I and pharmaceutically suitable salts, esters and prodrugs thereof which are useful as antibacterially effective tricyclic gyrase inhibitors. Pharmaceutical compositions, uses and related methods of preparing the compounds are also contemplated.resumo inibidores de girase tricíclica são aqui divulgados compostos tendo a estrutura de fórmula i e sais, ésteres e pró-fármacos farmaceuticamente adequados dos mesmos que são úteis como inibidores da girase tricíclica antibacterianamente eficazes. composições farmacêuticas, usos e métodos relacionados de preparação dos compostos são também contemplados.
