BARISH, MICHAEL,BROWN, CHRISTINE E.,FORMAN, STEPHEN J.,WANG, DONGRUI
申请号:
CA3001833
公开号:
CA3001833A1
申请日:
2016.10.13
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.