Michael Barish,Christine E. Brown,Stephen J. Forman,Dongrui Wang
申请号：
US15767960
公开号：
US20190389917A1
申请日:
2016.10.13
申请国别(地区):
US
年份:
2019
代理人:
摘要：
Chimeric transmembrane immunoreceptors (CAR) which include an extracellular domain that includes chlorotoxin or a related toxin, or a variant of chlorotoxin or a related toxin, that binds to human glioma or other human tumor cells, a transmembrane region, a costimulatory domain and an intracellular signaling domain are described.
