Vincent Brett Cooper,Kathryn Alanna Bradley,Samuel Robert Pygall,Rajan Gupta,Madison Paige Stanford,Lin Xie
申请号:
US14906085
公开号:
US09937153B2
申请日:
2014.08.25
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention is directed to stable, oral pharmaceutical formulations of dipeptidyl peptidase-4 inhibitors, such as omarigliptin. Such pharmaceutical formulations comprise omarigliptin and neutral excipients, wherein the neutral excipient is present in the amount of at least 75% by weight of the pharmaceutical formulation and comprises at least one non-reducible sugar diluent or a mixture of non-reducible sugar diluents.