Pharmaceutical composition in lyophilized dosage form and method for producing the same

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专利权人:

サミャン バイオファーマシューティカルズ コーポレイション

发明人:

ソ， ミン ヒョ,リー， サン ジュン,ソ, ミン ヒョ,リー, サン ジュン

申请号：

JP2011543438

公开号：

JP5372170B2

申请日:

2009.12.28

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

Disclosed is a pharmaceutical composition of a lyophilized formulation including a multiblock copolymer in which two or more ABA-type triblocks are covalently connected through biodegradable dicarboxylic linkage, wherein A represents a polyethylene oxide block and B represents a polypropylene oxide block, a polybutylene oxide block, or a block of copolymer of propylene oxide and butylene oxide, the multiblock copolymer being included in an amount of 1 to 7 wt % based on the total weight of solution prior to the lyophilized formulation. The composition is capable of reducing reconstitution time of a lyophilized sustained-release formulation.

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中国工程科技知识中心

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