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COMPOSITION PHARMACEUTIQUE D'UNE FORMULE LYOPHILISÉE ET SA MÉTHODE D'ÉLABORATION
专利权人:
SAMYANG BIOPHARMACEUTICALS CORPORATION
发明人:
申请号:
EP09836366.6
公开号:
EP2381929B1
申请日:
2009.12.28
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Disclosed is a pharmaceutical composition of a lyophilized formulation including a multiblock copolymer in which two or more ABA-type triblocks are covalently connected through biodegradable dicarboxylic linkage, wherein A represents a polyethylene oxide block and B represents a polypropylene oxide block, a polybutylene oxide block, or a block of copolymer of propylene oxide and butylene oxide, the multiblock copolymer being included in an amount of 1 to 7 wt % based on the total weight of solution prior to the lyophilized formulation. The composition is capable of reducing reconstitution time of a lyophilized sustained-release formulation.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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