Formula (I) compound of the bright Ti Gong mono- Seed of this Hair as Glucokinase Activation Elixirs, Drug Wu Group close object; And control Treatment by the be situated between Guide of glucokinase disease, Zhang Hinder or illness method.本發明提供一種作爲葡糖激酶活化劑的式(I)化合物,其藥物組合物;及治療由葡糖激酶所介導的疾病、障礙或病症的方法。