Compounds for the protection of sulfur containing linkers in nucleic acid synthesis

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专利权人:

Robert Duff

发明人:

Robert Duff

申请号：

US13189601

公开号：

US08673885B1

申请日:

2011.07.25

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Aromatic and alkyl thiocarbonates with and without a neighboring group that participates in the hydrolysis of a thiocarbonate are described. The aromatic or alkyl thiocarbonates can be used for the protection of sulfur during oligonucleotide synthesis. Their facile processes of manufacture and methods of using the same are provided.

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