Sabine Defays,Jag Paul Heer,Victoria Elizabeth Jackson,James Andrew Johnson,Boris Kroeplien,John Robert Porter
申请号：
US15038239
公开号：
US09969728B2
申请日:
2014.12.08
申请国别(地区):
US
年份:
2018
代理人:
摘要：
A series of substituted 5,6,7,8-tetrahydroimidazo[1,2-α]pyridine derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders； neurological and neurodegenerative disorders； pain and nociceptive disorders； cardiovascular disorders； metabolic disorders； ocular disorders； and oncological disorders.
