Universidad Nacional de Quilmes;Chemo Research, S.L.
发明人:
Pablo Lorenzano Menna,Daniel Fernando Alonso,Daniel Eduardo Gómez,Julieta Comin
申请号：
US14348577
公开号：
US09745257B2
申请日:
2012.10.10
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Provided herein are phenyl-guanidine derivatives for the inhibition of Rac1 which blocks its interaction with guanosine exchange factors (GEFs) belonging to the DBL family as agents for the treatment of aggressive and/or resistant tumors, as well as pharmaceutical compositions comprising them, their use in therapy and processes for their preparation.
